داستان آبیدیک

phosphorylated peptide


فارسی

1 عمومی:: پپتید فسفریل دار

In some cases, the antibody has a ratio of antibody binding to the phosphorylated peptide of SEQ-ID-NO:8 to antibody binding to the non-phosphorylated peptide of SEQ-ID-NO:69 of at least about 40. [0042] FIG. 3 illustrates the selective binding affinity of several anti-pS413-Tau antibodies for phosphorylated peptide PD17P, relative to non-phosphorylated peptide PD17, in accordance with some embodiments of the disclosure. [0047] FIG. 8A - FIG. 8D demonstrate that the parent mouse antibody (FIG. 8A and 8B) and the chimeric antibody (FIG. 8C and 8D) bind to a phosphorylated peptide (FIG. 8A and 8C) but not to the non-phosphorylated counterpart (FIG. 8B and 8D). In some embodiments, the KD value is measured with a phosphorylated peptide. , the phosphorylated Tau protein or the phosphorylated peptide) immobilized.

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